To evaluate the changes of immune system in CRF patients, plasma sII-2R level was measured in 10 healthy controls, 6 CRF patients not on hemodialysis (HD), 9 CRF patients on HD at pre and post HD using cuprophane (CUP0 dialyzer and 8 CRF patients
on HD
at pre HD and post HD using polymethylmethacrylate (PMMA) dialyzer. Serum sIL-2R level was measured usingd human-IL-2 receptor ELISA kit (Boehringer Mannheim Biochmical, Germany).
The results were as follow: plasma sIL-2R level was 274±108.7 pmol/L in CRF patient not on HD, 345±50.3 pmol/L in patients on HD usuing CUP dialyzer, 352.5±58.7 pmol/l in patients on HD using PMMA dialyzer and 124.8±40.2 pmol/l in healthy
controls.
On conclusion, serum sIL-2R level was higher in CRF patients than in healthy controls. Among the CRF patients serum sIL-2R level was higher in patients on HD than in patients not on HD(P<0.05). There were no difference between pre and post HD,
the
group
using CUP dialyzer and PMMA dialzyer.
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